This has been answered in different ways. This answer discusses which spider has killed the most people in the U.S. (the Black Widow) and also which spider has the deadliest venom (the Brazilian Wandering Spider). I’ve also attached a citation that shows the top 10 most poisonous spiders, again the Brazilian Wandering Spider takes the top spot.
The Sydney Funnel-web spider is often considered the world’s deadliest spider because it can kill a person with 15 minutes of the bite.
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