In Mesopotamia, art from about 2500 BCE depicts what researchers believe are the first domesticated buffalo. Depictions on pillars during the Shang Dynasty show they may have domesticated buffalo between 1766 and 1123 BCE. Skeletons of domesticated buffalo have been found in North-East Thailand dating from about 1600 BCE. So overall according to recorded world history, you could say we started domesticating them earliest in Mesopotamia in 2500 BCE, and it gradually spread around the continents as time passed.
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