The hole in the ozone layer is actually slowly getting better, but no thanks to the use of chlorofluorocarbons (CFCs), now regulated/phased out in many places. CFCs travel into the atmosphere and photodissociate, basically releasing halogen atoms that destroy ozone molecules.
CFCs were invented in the 1920s and mainly appeared in refrigeration units and aerosol spray propellants. The thickness of the ozone layer also naturally increases in the spring due to seasonal variations of sunlight intensity, and atmospheric circulation patterns.
Like elifitz stated, CFCs are a cause of the depletion of the ozone layer. This can be hazardous because the ozone layer is what protects the earth from UV rays. Fortunately we have found ways to avoid the use of CFCs, which will hopefully prevent further harm or damage to the ozone layer.
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