This would fall under the Quaternary extinction event, the main causes for which are considered to be climate changes (ending ice age) and overhunting by early humans. In North America, over 50,000 years, 33 genera of large mammals have gone extinct. 15 of those happened around 11,500-10,000 years ago – soon after the arrival of humans (13,000 years ago according to other sources). Some of the examples are mammoths, American mastodons, camels, horses, stag-moose, giant sloths and beavers, saber-tooth cats, short-faced bears, American cheetah, American lion, and dire wolves.
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