I checked the Material Safety Data Sheets (MSDS) for several acrylic nail powders, and while these powdered acrylics are not know to cause severe health problems, it is recommended that you avoid inhalation. The dust can irritate your lungs and throat, as well as your nose. If you do inhale the substance, the forms recommend that you seek fresh air until you are no longer uncomfortable. Generally, it is good advice not to inhale any powder, but acrylic powder is not necessarily more harmful than others.
It is not listed as a carcinogen by the IARC, NTP, ACIGH, or OSHA. However, inhaling powdered acrylic may have serious side effects, not limited to irritation of the respiratory tract, coughing, dizziness, headache, confusion, incoordination, and loss of consciousness. As with any inhalant, even moderate use can lead to blackouts and thus to brain damage. Therefore, powdered acrylic is not considered safe to inhale.
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