It depends what is in it! The “if it’s yellow, let it mellow” rule applies here. Urine is even safe to drink (http://healthlibrary.epnet.com/GetContent.aspx?token=5344349d-8fbc-446e-8ae5-03a924025f8c&chunkiid=161688), so if there’s any splashback onto a person sitting on the toilet, it’s less of a health hazard. However, poop is full of bacteria, and once it hits a toilet it should be flushed away to avoid the spread of disease.
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