This varies by individual. I had to stop drinking any coffee because the caffeine was effecting my heart rhythm. Clearly, this doesn’t happen to everyone.
The first link below gives this list as symptoms of someone in caffeine intoxication: “restlessness, nervousness, excitement, insomnia, flushed face, diuresis, and gastrointestinal complaints.”
In addition, death is possible from too much caffeine. According to the link below, too much is 10 grams of caffeine, or 80-100 cups of coffee. The article describes a caffeine death.
The second link below is to a great blog post about one person’s experiences with caffeine and giving up coffee.
Caffeine affects everyone differently, although in moderate doses (between 200 to 300 milligrams a day, which is equivalent to two to four cups of coffee), caffeine is not harmful to an otherwise healthy person. A heavy caffeine intake (anything above 500 to 600 milligrams a day, which is equivalent to five to seven cups of coffee) can start to cause insomnia, restlessness, headaches, anxiety, and an irregular heartbeat.
It depends on the person. I am an avid coffee drinker, and the general rule is to avoid “the jitters.” If you have the jitters, the only way to cure it is to wait it out, though eating fatty or starchy foods will slow the entry of more caffeine still in your stomach into your bloodstream, and might soften the blow by shortening recovery time and alleviating gastrointestinal irritation.
Usually it’s up tot the individual to determine an appropriate caffeine intake. If you are having problems sleeping, with anxiety, nausea, muscle tension, irritability, or withdrawal symptoms like headaches, you might consider cutting back, even just to see if these symptoms alleviate by doing so.
Most people don’t generally view caffeine as a good substance to ingest, however do keep in mind that some forms of caffeine in small doses can be beneficial as well. Coffee, for example, has some great health benefits despite its bad reputation. It has been linked to lower occurance of type 2 diabetes and some forms of dementia in addition to a lower occurance of some kinds of cancer. Coffee, or caffeine in general, in small doses is also thought to have some pain-reducing effects. Don’t take this to mean that 10 cups of coffee a day are fine, but one or two cups are okay.
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