How does tick saliva keep mice from getting Lyme disease?



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    When the bacterium that causes Lyme disease travels through a tick’s body, it is covered in a thick saliva that contains the protein we call Salp15. This protein prevents the tick from being infected itself, and aids in infection of the host. When Salp15 is injected into mice, they are protected from Lyme disease. This discovery shows great promise for the development of a vaccine not only for Lyme disease, but for other harmful bacteria spread through parasites.

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