There are numerous potential effects on humans from pesticides. These effects can include detrimental damage to the nervous system, irritation of skin or eyes, acting as carcinogens and effecting the hormone and endorcrine systems.
In most cases though, the amount of pesticides people are exposed to are too small to pose a risk.
As Jmendez said, the effects of pesticides on human health are vast and far reaching. In the link attached are more details about the specific threats, although jmendez pointed out the most central ones. For anyone interested in this issue, Silent Spring by Rachel Carson is a must ride, as it was the book that is credited in helping spark the environmental movement.
Here are some previous GreenAnswers questions with detailed answers on the effects of pesticides on human health:
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