Critics of genetically modified crops maintain that genetically-identical cloned crop populations, while they may be engineered for heartiness, are actually more vulnerable to total crop loss from unexpected weather changes, disease, fungus, etc. Since modified crops have little genetic diversity, if something can kill off one, it can kill off the entire population. In more diverse crops, some members of the population will likely contain genetic variations that help them survive and repopulate.
Modified crops also run the risk of entering the wild and competing with native populations. This may result in native populations being overrun by the modified crops, once again leading to an increased risk of total crop loss.
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