Secretions from some frogs found out west (such as the Colorado River Toad) have been known to cause hallucinations and have subsequently been used as recreational drugs (have you ever seen that episode of south park involving cats and “cheesing”, it was making fun of people who like those toads, Family Guy also did an episode on it).
As far as truly poisonous frogs, there may be a few in America but they are mostly found in other areas (the Amazon, for example, is abundant with poisonous frogs).
may be a few
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