Yes, spray pheromones do calm down pets, and are especially useful for car trips or when a pet is abnormally perturbed. It can also be used to treat urine marking. Animals do respond differently to them, though. Pheromones are naturally released by cats as chemical substances, and cats use them to familiarize themselves with their surroundings. Pheromone sprays contain mostly ethanol as the liquid base. There are some natural herb pheromone sprays that would be more eco-friendly than others.
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