Yes we can have a type of natural selection, normally determined by disease. For example some believe that the plague was in a way, natural selection due to people that actually survived and genes some of us that descended from them have in our DNA.
I think it goes beyond just disease resistance. Whether or not you realize it, when you’re looking for a mate there are hundreds of things you take into consideration on a semi- or even sub-consious level. Things like: do their pheromone levels meet my needs, are they a specimen of the species that will produce sufficient offspring? This goes beyond do they stink or not and do they look good and are they smart. It’s a biological imperative to find the best possible mate. This serves both the individual’s needs and the species needs to move the species forward.
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