If you mean genetically modified organisms, the pumpkins in stores now could already be considered GMOs. Like we have with virtually all domesticated plants and animals, we have artificially selected for certain traits in pumpkins including color, flavor and size. Competitive pumpkin-growers continue to selectively breed for size, although this usually meanssacrificing some of the beauty and flavor of the pumpkin.
Of course, pumpkins can also be altered using more direct genetic manipulation, as evidenced by the many organic pumpkin products that must advertise that they are non-GMO. But given the amount of time we have been growing pumpkins, we seem to be able to grow them pretty huge without that kind of technology.
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