The extract from the bark of the plant caused paralysis in a toad in an experiment. The fruits, however, can be eaten safely when ripe, including the seeds. The seed shells are hard enough not to get digested, but the kernel inside is toxic. In addition, leaves, young fruits, and the seeds can be used as insecticide. Even the sap from branches causes irritation and can cause severe damage to eyes.
The cherimoya is known by many names, it is also called the custard apple, or the mamon, or kasjoema. And yes, the kernels are toxic. The leaves, twigs, and fruit are all natural insectisides, and the bark when injected is a paralytic.
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