Not in the sense of: Can we clean up Los Angeles with a big purifier?
But it’s an interesting question, because you need to be able to answer similar ones to design long-term spacecraft, and to terraform planets.
Another similar situation is the Biosphere 2 (A major experiment, not to be missed.) It was the only large scale biosphere, so far. It’s a completely enclosed small community, except for the sunlight coming in.
And, for something different, take a look at the simple system in the EcoSphere. No air filter at all, in a sense, because nothing except energy gets in, and nothing gets out, except heat. (Interesting. Think I’m going to buy one.)
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