Yes, people can be born with a large heart. At birth, an enlarged heart is caused by a congenital health defect. These defects can affect blood flow through the heart, causing the heart to pump harder and thus enlarging the heart.
Other reasons for having an enlarged heart at any point in your life are: high blood pressure, heart valve disease, cardiomyopathy, heart attack, arrythmia, pulmonary hypertension, anemia, thyroid diseases, hemachromatosis, and rare diseases that affect your heart.
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